Syphilis is a bacterial infection usually spread by sexual contact. This test screens for syphilis, an infection that leads to sores on the penis and vagina , rashes, and lesions on your body .
The disease starts as a painless sore — typically on the genitals, rectum or mouth. Syphilis spreads from person to person via skin or mucous membrane contact with these sore. here may also be sores in the mouth or vagina. In latent syphilis, which can last for years, there are few or no symptoms. In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms.